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Lewis J Frey, PhD
Associate Professor of Public Health Sciences
College of Medicine
MUSC

Email: frey@musc.edu
 
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Lewis J Frey, PhD

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Research Interest:

My research interests include the development of novel algorithms and information systems for the purpose of discovery and data integration applicable to precision medicine. In addition to applying novel machine learning to medically relevant data, my information systems approach combines the accumulated wealth of knowledge that exists in medical record systems with the vast amounts of molecular data being captured with high-throughput measurement technologies. Currently, I am focused on the investigation of the utility of novel similarity measures to conduct predictive analytics.

Selected Publications:

1.Guo JW, Sward K, Beck S, Wong B, Staggers N, Frey L. Using a content analysis to identify study eligibility criteria concepts in cancer nursing research. Comput Inform Nurs. .32(7):333-42, 2014.
View in: PubMed

2.Piccolo SR, Frey LJ. Clinical and molecular models of glioblastoma multiforme survival. Int J Data Min Bioinform. .7(3):245-65, 2013. PMCID: PMC4018825
View in: PubMed

3.Frey LJ, Piccolo SR, Edgerton ME. Multiplicity: an organizing principle for cancers and somatic mutations. BMC Med Genomics. .4:52, 2011. PMCID: PMC3150236
View in: PubMed

4.Cryer ME, Frey L. Agent-based modeling supporting the migration of registry systems to grid based architectures. Summit on Translat Bioinforma. .2009:26-30, 2009. PMCID: PMC3041565
View in: PubMed

5.Kunz I, Lin MC, Frey L. Metadata mapping and reuse in caBIG. BMC Bioinformatics. .10 Suppl 2:S4, 2009. PMCID: PMC2646244
View in: PubMed

6.Piccolo SR, Frey LJ. Somatic mutation signatures of cancer. AMIA Annu Symp Proc. .202-6, 2008. PMCID: PMC2655983
View in: PubMed

7.Edgerton ME, Fisher DH, Tang L, Frey LJ, Chen Z. Data mining for gene networks relevant to poor prognosis in lung cancer via backward-chaining rule induction. Cancer Inform. .3:93-114, 2007. PMCID: PMC2312096
View in: PubMed

8.Frey LJ, Maojo V, Mitchell JA. Bioinformatics linkage of heterogeneous clinical and genomic information in support of personalized medicine. Yearb Med Inform. .98-105, 2007.
View in: PubMed

9.Frey L, Edgerton M, Fisher D, Levy S. Ensemble stump classifiers and gene expression signatures in lung cancer. Stud Health Technol Inform. .129(Pt 2):1255-9, 2007.
View in: PubMed

10.Frey L, Edgerton ME, Fisher DH, Tang L, Chen Z. Using prior knowledge and rule induction methods to discover molecular markers of prognosis in lung cancer. AMIA Annu Symp Proc. .256-60, 2005. PMCID: PMC1560786
View in: PubMed