Hollings Home  
 
Stephen P Ethier, PhD
Professor of Pathology & Laboratory Medicine
College of Medicine
MUSC

Email: ethier@musc.edu
 
       Print This Page
       
 
 


 

Stephen P Ethier, PhD

Return to Search Page  

Research Interest:

Dr. Ethier's laboratory examines the mechanisms by which oncogenes transform human mammary epithelial cells and play a role in breast cancer development. Over the past ten years, Dr. Ethier's laboratory has developed a strong interest in breast cancer genomics. He has focused his efforts on understanding the oncogenes that are present on the 8p11 amplicon, which occurs in approximately 15% of human breast cancers and is exclusively seen in the most aggressive luminal B type breast cancers. WHSC1l1, DDHD2, and LSM1 are among the key oncogenes his laboratory has identified from these studies. Finally, he has incorporated the use of genome-scale shRNA screening strategies to identify other key breast cancer oncogenes that play important roles in breast cancer development and interact with other more well-known oncogenes to induce malignant transformation.

Honors:
Countess Alicia Spaulding-Paolozzi Distinguished Endowed Chair in Breast Cancer Diagnosis, Treatment, and Research

Positions:
Director, Center for Genomic Medicine, Medical University of South Carolina
Scientific Director, Genomics Shared Resource, Hollings Cancer Center, Medical University of South Carolina

Selected Publications:

1.Freedman LP, Gibson MC, Wisman R, Ethier SP, Soule HR, Reid YA, Neve RM. The culture of cell culture practices and authentication-Results from a 2015 Survey. Biotechniques. .59(4):189-92, 2015. PMID: 26458546
View in: PubMed

2.Mehmeti M, Allaoui R, Bergenfelz C, Saal LH, Ethier SP, Johansson ME, Jirström K, Leandersson K. Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer. Breast Cancer Res. .17(1):130, 2015. PMID: 26392082 PMCID: PMC4578669
View in: PubMed

3.Freedman LP, Gibson MC, Ethier SP, Soule HR, Neve RM, Reid YA. Reproducibility: changing the policies and culture of cell line authentication. Nat Methods. .12(6):493-7, 2015. PMID: 26020501
View in: PubMed

4.Williams CB, Soloff AC, Ethier SP, Yeh ES. Perspectives on Epidermal Growth Factor Receptor Regulation in Triple-Negative Breast Cancer: Ligand-Mediated Mechanisms of Receptor Regulation and Potential for Clinical Targeting. Adv Cancer Res. .127:253-81, 2015. PMID: 26093903
View in: PubMed

5.Guest ST, Kratche ZR, Bollig-Fischer A, Haddad R, Ethier SP. Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes. Exp Cell Res. .332(2):223-35, 2015. PMID: 25704758
View in: PubMed

6.Kappler CS, Guest ST, Irish JC, Garrett-Mayer E, Kratche Z, Wilson RC, Ethier SP. Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer. Mol Oncol. .9(2):527-43, 2014. PMID: 25454348 PMCID: PMC4304881
View in: PubMed

7.Findlay VJ, Wang C, Nogueira LM, Hurst K, Quirk D, Ethier SP, Staveley O'Carroll KF, Watson DK, Camp ER. SNAI2 modulates colorectal cancer 5-fluorouracil sensitivity through miR145 repression. Mol Cancer Ther. .13(11):2713-26, 2014. PMID: 25249558 PMCID: PMC4221636
View in: PubMed

8.Turner-Ivey B, Guest ST, Irish JC, Kappler CS, Garrett-Mayer E, Wilson RC, Ethier SP. KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer. Neoplasia. .16(8):644-55, 2014. PMID: 25220592 PMCID: PMC4234874
View in: PubMed

9.Timmerman LA, Holton T, Yuneva M, Louie RJ, Padró M, Daemen A, Hu M, Chan DA, Ethier SP, van 't Veer LJ, Polyak K, McCormick F, Gray JW. Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. Cancer Cell. .24(4):450-65, 2013. PMID: 24094812 PMCID: PMC3931310
View in: PubMed

10.Holm K, Grabau D, Lövgren K, Aradottir S, Gruvberger-Saal S, Howlin J, Saal LH, Ethier SP, Bendahl PO, Stål O, Malmström P, Fernö M, Rydén L, Hegardt C, Borg Å, Ringnér M. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. Mol Oncol. .6(5):494-506, 2012. PMID: 22766277
View in: PubMed

11.Wang G, Liu G, Wang X, Sethi S, Ali-Fehmi R, Abrams J, Zheng Z, Zhang K, Ethier S, Yang ZQ. ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways. BMC Cancer. .12:225, 2012. PMID: 22681620 PMCID: PMC3732090
View in: PubMed

12.Piechocki MP, Wu GS, Jones RF, Jacob JB, Gibson H, Ethier SP, Abrams J, Yagita H, Venuprasad K, Wei WZ. Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA. Int J Cancer. .131(11):2562-72, 2012. PMID: 22419388 PMCID: PMC3387508
View in: PubMed

13.Baillo A, Giroux C, Ethier SP. Knock-down of amphiregulin inhibits cellular invasion in inflammatory breast cancer. J Cell Physiol. .226(10):2691-701, 2011. PMID: 21302279 PMCID: PMC3865809
View in: PubMed

14.Fackler MJ, Umbricht CB, Williams D, Argani P, Cruz LA, Merino VF, Teo WW, Zhang Z, Huang P, Visvananthan K, Marks J, Ethier S, Gray JW, Wolff AC, Cope LM, Sukumar S. Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence. Cancer Res. .71(19):6195-207, 2011. PMID: 21825015 PMCID: PMC3308629
View in: PubMed

15.Wu J, Liu S, Liu G, Dombkowski A, Abrams J, Martin-Trevino R, Wicha MS, Ethier SP, Yang ZQ. Identification and functional analysis of 9p24 amplified genes in human breast cancer. Oncogene. .31(3):333-41, 2011. PMID: 21666724 PMCID: PMC3886828
View in: PubMed

16.Bollig-Fischer A, Dewey TG, Ethier SP. Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells. PLoS One. .6(3):e17959, 2011. PMID: 21437235 PMCID: PMC3060101
View in: PubMed

17.Cote ML, Haddad R, Edwards DJ, Atikukke G, Gadgeel S, Soubani AO, Lonardo F, Bepler G, Schwartz AG, Ethier SP. Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer. J Thorac Oncol. .6(3):627-30, 2011. PMID: 21317742 PMCID: PMC3057407
View in: PubMed

18.Zhang H, Meng F, Liu G, Zhang B, Zhu J, Wu F, Ethier SP, Miller F, Wu G. Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res. .71(4):1292-301, 2011. PMID: 21285253 PMCID: PMC3906209
View in: PubMed

19.Yang ZQ, Liu G, Bollig-Fischer A, Giroux CN, Ethier SP. Transforming properties of 8p11-12 amplified genes in human breast cancer. Cancer Res. .70(21):8487-97, 2010. PMID: 20940404 PMCID: PMC3089754
View in: PubMed

20.Bollig-Fischer A, Dziubinski M, Boyer A, Haddad R, Giroux CN, Ethier SP. HER-2 signaling, acquisition of growth factor independence, and regulation of biological networks associated with cell transformation. Cancer Res. .70(20):7862-73, 2010. PMID: 20736364 PMCID: PMC3858175
View in: PubMed

21.Mueller KL, Yang ZQ, Haddad R, Ethier SP, Boerner JL. EGFR/Met association regulates EGFR TKI resistance in breast cancer. J Mol Signal. .5:8, 2010. PMID: 20624308 PMCID: PMC2911419
View in: PubMed

22.Zhang H, Chen D, Ringler J, Chen W, Cui QC, Ethier SP, Dou QP, Wu G. Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo. Cancer Res. .70(10):3996-4004, 2010. PMID: 20424113 PMCID: PMC3827685
View in: PubMed

23.Yang ZQ, Liu G, Bollig-Fischer A, Haddad R, Tarca AL, Ethier SP. Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers. Int J Cancer. .125(7):1613-21, 2009. PMID: 19569235 PMCID: PMC2735097
View in: PubMed

24.Liu G, Bollig-Fischer A, Kreike B, van de Vijver MJ, Abrams J, Ethier SP, Yang ZQ. Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer. Oncogene. .28(50):4491-500, 2009. PMID: 19784073 PMCID: PMC2795798
View in: PubMed

25.Hollestelle A, Nagel JH, Smid M, Lam S, Elstrodt F, Wasielewski M, Ng SS, French PJ, Peeters JK, Rozendaal MJ, Riaz M, Koopman DG, Ten Hagen TL, de Leeuw BH, Zwarthoff EC, Teunisse A, van der Spek PJ, Klijn JG, Dinjens WN, Ethier SP, Clevers H, Jochemsen AG, den Bakker MA, Foekens JA, Martens JW, Schutte M. Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines. Breast Cancer Res Treat. .121(1):53-64, 2009. PMID: 19593635
View in: PubMed

26.Arias-Romero LE, Saha S, Villamar-Cruz O, Yip SC, Ethier SP, Zhang ZY, Chernoff J. Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells. Cancer Res. .69(11):4582-8, 2009. PMID: 19435911 PMCID: PMC2692630
View in: PubMed

27.Lippman ME, Ethier S, Hayes DF. Editorial: Cost-effective analyses in Breast Cancer Research and Treatment [corrected]. Breast Cancer Res Treat. .115(2):221-2, 2009. PMID: 19449205
View in: PubMed

28.Balan V, Nangia-Makker P, Schwartz AG, Jung YS, Tait L, Hogan V, Raz T, Wang Y, Yang ZQ, Wu GS, Guo Y, Li H, Abrams J, Couch FJ, Lingle WL, Lloyd RV, Ethier SP, Tainsky MA, Raz A. Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study. Cancer Res. .68(24):10045-50, 2008. PMID: 19074869 PMCID: PMC2882172
View in: PubMed

29.Riggins RB, Lan JP, Zhu Y, Klimach U, Zwart A, Cavalli LR, Haddad BR, Chen L, Gong T, Xuan J, Ethier SP, Clarke R. ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. Cancer Res. .68(21):8908-17, 2008. PMID: 18974135 PMCID: PMC2701641
View in: PubMed

30.Willmarth NE, Baillo A, Dziubinski ML, Wilson K, Riese DJ, Ethier SP. Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop. Cell Signal. .21(2):212-9, 2008. PMID: 18951974 PMCID: PMC2632975
View in: PubMed

31.Mueller KL, Hunter LA, Ethier SP, Boerner JL. Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells. Cancer Res. .68(9):3314-22, 2008. PMID: 18451158 PMCID: PMC3878202
View in: PubMed

32.Willmarth NE, Ethier SP. Amphiregulin as a novel target for breast cancer therapy. J Mammary Gland Biol Neoplasia. .13(2):171-9, 2008. PMID: 18437539
View in: PubMed

33.Wasielewski M, Hanifi-Moghaddam P, Hollestelle A, Merajver SD, van den Ouweland A, Klijn JG, Ethier SP, Schutte M. Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines. Breast Cancer Res Treat. .113(2):285-91, 2008. PMID: 18297428
View in: PubMed

34.Zhang H, Liu G, Dziubinski M, Yang Z, Ethier SP, Wu G. Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res Treat. .112(2):217-27, 2007. PMID: 18074223
View in: PubMed

35.Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, Memeo L, Ludwig T, Ethier SP, Krogh M, Szabolcs M, Murty VV, Isola J, Hibshoosh H, Parsons R, Borg A. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nat Genet. .40(1):102-7, 2007. PMID: 18066063 PMCID: PMC3018354
View in: PubMed

36.Draghici S, Tarca AL, Yu L, Ethier S, Romero R. KUTE-BASE: storing, downloading and exporting MIAME-compliant microarray experiments in minutes rather than hours. Bioinformatics. .24(5):738-40, 2007. PMID: 18024967 PMCID: PMC2386582
View in: PubMed

37.Yang ZQ, Moffa AB, Haddad R, Streicher KL, Ethier SP. Transforming properties of TC-1 in human breast cancer: interaction with FGFR2 and beta-catenin signaling pathways. Int J Cancer. .121(6):1265-73, 2007. PMID: 17520678
View in: PubMed

38.Streicher KL, Willmarth NE, Garcia J, Boerner JL, Dewey TG, Ethier SP. Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells. Mol Cancer Res. .5(8):847-61, 2007. PMID: 17670913
View in: PubMed

39.Diehl KM, Grewal N, Ethier SP, Woods-Ignatoski KM. p38MAPK-activated AKT in HER-2 overexpressing human breast cancer cells acts as an EGF-independent survival signal. J Surg Res. .142(1):162-9, 2007. PMID: 17612563
View in: PubMed

40.Wu G, Guo Z, Chang X, Kim MS, Nagpal JK, Liu J, Maki JM, Kivirikko KI, Ethier SP, Trink B, Sidransky D. LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer. Cancer Res. .67(9):4123-9, 2007. PMID: 17456585
View in: PubMed

41.Moffa AB, Ethier SP. Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells. J Cell Physiol. .210(3):720-31, 2007. PMID: 17133345
View in: PubMed

42.Yang ZQ, Streicher KL, Ray ME, Abrams J, Ethier SP. Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer. Cancer Res. .66(24):11632-43, 2006. PMID: 17178857
View in: PubMed

43.Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe JP, Tong F, Speed T, Spellman PT, DeVries S, Lapuk A, Wang NJ, Kuo WL, Stilwell JL, Pinkel D, Albertson DG, Waldman FM, McCormick F, Dickson RB, Johnson MD, Lippman M, Ethier S, Gazdar A, Gray JW. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. .10(6):515-27, 2006. PMID: 17157791 PMCID: PMC2730521
View in: PubMed

44.Willmarth NE, Ethier SP. Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells. J Biol Chem. .281(49):37728-37, 2006. PMID: 17035230
View in: PubMed

45.Streicher KL, Yang ZQ, Draghici S, Ethier SP. Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon. Oncogene. .26(14):2104-14, 2006. PMID: 17001308 PMCID: PMC2435249
View in: PubMed

46.Hayes DF, Ethier S, Lippman ME. New guidelines for reporting of tumor marker studies in breast cancer research and treatment: REMARK. Breast Cancer Res Treat. .100(2):237-8, 2006. PMID: 16773436
View in: PubMed

47.Pal M, Moffa A, Sreekumar A, Ethier SP, Barder TJ, Chinnaiyan A, Lubman DM. Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation. Anal Chem. .78(3):702-10, 2006. PMID: 16448042
View in: PubMed

48.Elstrodt F, Hollestelle A, Nagel JH, Gorin M, Wasielewski M, van den Ouweland A, Merajver SD, Ethier SP, Schutte M. BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three new deleterious mutants. Cancer Res. .66(1):41-5, 2006. PMID: 16397213
View in: PubMed

49.Gelsi-Boyer V, Orsetti B, Cervera N, Finetti P, Sircoulomb F, Rougé C, Lasorsa L, Letessier A, Ginestier C, Monville F, Esteyriès S, Adélaïde J, Esterni B, Henry C, Ethier SP, Bibeau F, Mozziconacci MJ, Charafe-Jauffret E, Jacquemier J, Bertucci F, Birnbaum D, Theillet C, Chaffanet M. Comprehensive profiling of 8p11-12 amplification in breast cancer. Mol Cancer Res. .3(12):655-67, 2005. PMID: 16380503
View in: PubMed

50.Woods Ignatoski KM, Dziubinski ML, Ammerman C, Ethier SP. Cooperative interactions of HER-2 and HPV-16 oncoproteins in the malignant transformation of human mammary epithelial cells. Neoplasia. .7(8):788-98, 2005. PMID: 16207481 PMCID: PMC1501888
View in: PubMed

51.Berquin IM, Pang B, Dziubinski ML, Scott LM, Chen YQ, Nolan GP, Ethier SP. Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells. Oncogene. .24(19):3177-86, 2005. PMID: 15735691
View in: PubMed

52.Jia Y, Zeng ZZ, Markwart SM, Rockwood KF, Ignatoski KM, Ethier SP, Livant DL. Integrin fibronectin receptors in matrix metalloproteinase-1-dependent invasion by breast cancer and mammary epithelial cells. Cancer Res. .64(23):8674-81, 2004. PMID: 15574776
View in: PubMed

53.Yang ZQ, Albertson D, Ethier SP. Genomic organization of the 8p11-p12 amplicon in three breast cancer cell lines. Cancer Genet Cytogenet. .155(1):57-62, 2004. PMID: 15527903
View in: PubMed

54.Moffa AB, Tannheimer SL, Ethier SP. Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells. Mol Cancer Res. .2(11):643-52, 2004. PMID: 15561780
View in: PubMed

55.Rios-Doria J, Kuefer R, Ethier SP, Day ML. Cleavage of beta-catenin by calpain in prostate and mammary tumor cells. Cancer Res. .64(20):7237-40, 2004. PMID: 15492240
View in: PubMed

56.Willmarth NE, Albertson DG, Ethier SP. Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells. Breast Cancer Res. .6(5):R531-9, 2004. PMID: 15318934 PMCID: PMC549168
View in: PubMed

57.Song H, Ethier SP, Dziubinski ML, Lin J. Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells. Biochem Biophys Res Commun. .314(1):143-50, 2004. PMID: 14715258
View in: PubMed

58.Nyati MK, Maheshwari D, Hanasoge S, Sreekumar A, Rynkiewicz SD, Chinnaiyan AM, Leopold WR, Ethier SP, Lawrence TS. Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo. Clin Cancer Res. .10(2):691-700, 2004. PMID: 14760092
View in: PubMed

59.Ray ME, Yang ZQ, Albertson D, Kleer CG, Washburn JG, Macoska JA, Ethier SP. Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines. Cancer Res. .64(1):40-7, 2004. PMID: 14729606
View in: PubMed

60.Woods Ignatoski KM, Livant DL, Markwart S, Grewal NK, Ethier SP. The role of phosphatidylinositol 3'-kinase and its downstream signals in erbB-2-mediated transformation. Mol Cancer Res. .1(7):551-60, 2003. PMID: 12754302
View in: PubMed

61.Ethier SP. Identifying and validating causal genetic alterations in human breast cancer. Breast Cancer Res Treat. .78(3):285-7, 2003. PMID: 12755487
View in: PubMed

62.Woods Ignatoski KM, Grewal NK, Markwart S, Livant DL, Ethier SP. p38MAPK induces cell surface alpha4 integrin downregulation to facilitate erbB-2-mediated invasion. Neoplasia. .5(2):128-34, 2003. PMID: 12659685 PMCID: PMC1550346
View in: PubMed

63.Kumar-Sinha C, Ignatoski KW, Lippman ME, Ethier SP, Chinnaiyan AM. Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis. Cancer Res. .63(1):132-9, 2003. PMID: 12517789
View in: PubMed

64.Popovici C, Basset C, Bertucci F, Orsetti B, Adélaide J, Mozziconacci MJ, Conte N, Murati A, Ginestier C, Charafe-Jauffret E, Ethier SP, Lafage-Pochitaloff M, Theillet C, Birnbaum D, Chaffanet M. Reciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene. Genes Chromosomes Cancer. .35(3):204-18, 2002. PMID: 12353263
View in: PubMed

65.Billecke CA, Ljungman ME, McKay BC, Rehemtulla A, Taneja N, Ethier SP. Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells. Oncogene. .21(29):4481-9, 2002. PMID: 12085226
View in: PubMed

66.Ethier SP. Signal transduction pathways: the molecular basis for targeted therapies. Semin Radiat Oncol. .12(3 Suppl 2):3-10, 2002. PMID: 12174339
View in: PubMed

67.Ram TG, Hosick HL, Ethier SP. Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells. J Cell Physiol. .183(3):301-13, 2000. PMID: 10797304
View in: PubMed

68.Ignatoski KM, Maehama T, Markwart SM, Dixon JE, Livant DL, Ethier SP. ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells. Br J Cancer. .82(3):666-74, 2000. PMID: 10682681 PMCID: PMC2363331
View in: PubMed

69.Forozan F, Veldman R, Ammerman CA, Parsa NZ, Kallioniemi A, Kallioniemi OP, Ethier SP. Molecular cytogenetic analysis of 11 new breast cancer cell lines. Br J Cancer. .81(8):1328-34, 1999. PMID: 10604729 PMCID: PMC2362964
View in: PubMed

70.Ignatoski KM, Ethier SP. Constitutive activation of pp125fak in newly isolated human breast cancer cell lines. Breast Cancer Res Treat. .54(2):173-82, 1999. PMID: 10424408
View in: PubMed

71.Aprelikova O, Kuthiala A, Bessho M, Ethier S, Liu ET. BRCA1 protein level is not affected by peptide growth factors in MCF10A cell line. Oncogene. .13(11):2487-91, 1996. PMID: 8957093
View in: PubMed

72.Ethier SP, Kokeny KE, Ridings JW, Dilts CA. erbB family receptor expression and growth regulation in a newly isolated human breast cancer cell line. Cancer Res. .56(4):899-907, 1996. PMID: 8631031
View in: PubMed

73.Ethier SP, Mahacek ML, Gullick WJ, Frank TS, Weber BL. Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media. Cancer Res. .53(3):627-35, 1993. PMID: 8425198
View in: PubMed

74.Ethier SP, Summerfelt RM, Cundiff KC, Asch BB. The influence of growth factors on the proliferative potential of normal and primary breast cancer-derived human breast epithelial cells. Breast Cancer Res Treat. .17(3):221-30, 1991. PMID: 1710154
View in: PubMed

75.Ethier SP, Cundiff KC. Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells. Cancer Res. .47(20):5316-22, 1987. PMID: 3115564
View in: PubMed

76.Ethier SP, Kudla A, Cundiff KC. Influence of hormone and growth factor interactions on the proliferative potential of normal rat mammary epithelial cells in vitro. J Cell Physiol. .132(1):161-7, 1987. PMID: 2439521
View in: PubMed

77.Ethier SP. Serum-free culture conditions for the growth of normal rat mammary epithelial cells in primary culture. In Vitro Cell Dev Biol. .22(8):485-90, 1986. PMID: 3488312
View in: PubMed