Research Interest:
Dysregulation of the IGF system in cancer; IGF binding protein structure and function
Selected Publications:
| 1. | Rossa C, Sommer G, Spolidorio LC, Rosenzweig SA, Watson DK, Kirkwood KL. Loss of expression and function of SOCS3 is an early event in HNSCC: altered subcellular localization as a possible mechanism involved in proliferation, migration and invasion. PLoS One. .7(9):e45197, 2012. PMCID: PMC3445460
View in: PubMed
| | 2. | Rosenzweig SA. Acquired resistance to drugs targeting receptor tyrosine kinases. Biochem Pharmacol. .83(8):1041-8, 2011. PMCID: PMC3299940
View in: PubMed
| | 3. | Rosenzweig SA, Atreya HS. Defining the pathway to insulin-like growth factor system targeting in cancer. Biochem Pharmacol. .80(8):1115-24, 2010. PMCID: PMC2934757
View in: PubMed
| | 4. | Swain M, Slomiany MG, Rosenzweig SA, Atreya HS. High-yield bacterial expression and structural characterization of recombinant human insulin-like growth factor binding protein-2. Arch Biochem Biophys. .501(2):195-200, 2010. PMCID: PMC2934857
View in: PubMed
| | 5. | Lucas JT, Salimath BP, Slomiany MG, Rosenzweig SA. Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent. Oncogene. .29(31):4449-59, 2010. PMCID: PMC2921319
View in: PubMed
| | 6. | Mulligan JK, Rosenzweig SA, Young MR. Tumor secretion of VEGF induces endothelial cells to suppress T cell functions through the production of PGE2. J Immunother. .33(2):126-35, 2010. PMCID: PMC3333835
View in: PubMed
| | 7. | Swain M, Thirupathi R, Krishnarjuna B, Eaton EM, Kibbey MM, Rosenzweig SA, Atreya HS. Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures. Chem Commun (Camb). .46(2):216-8, 2009.
View in: PubMed
| | 8. | Mulligan JK, Day TA, Gillespie MB, Rosenzweig SA, Young MR. Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions. Hum Immunol. .70(6):375-82, 2009. PMCID: PMC2746465
View in: PubMed
| | 9. | Slomiany MG, Black LA, Kibbey MM, Tingler MA, Day TA, Rosenzweig SA. Insulin-like growth factor-1 receptor and ligand targeting in head and neck squamous cell carcinoma. Cancer Lett. .248(2):269-79, 2006.
View in: PubMed
| | 10. | Slomiany MG, Rosenzweig SA. Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion. J Pharmacol Exp Ther. .318(2):666-75, 2006.
View in: PubMed
| | 11. | Robinson SA, Rosenzweig SA. Paradoxical effects of the phage display-derived peptide antagonist IGF-F1-1 on insulin-like growth factor-1 receptor signaling. Biochem Pharmacol. .72(1):53-61, 2006.
View in: PubMed
| | 12. | Slomiany MG, Black LA, Kibbey MM, Day TA, Rosenzweig SA. IGF-1 induced vascular endothelial growth factor secretion in head and neck squamous cell carcinoma. Biochem Biophys Res Commun. .342(3):851-8, 2006.
View in: PubMed
| | 13. | Kibbey MM, Jameson MJ, Eaton EM, Rosenzweig SA. Insulin-like growth factor binding protein-2: contributions of the C-terminal domain to insulin-like growth factor-1 binding. Mol Pharmacol. .69(3):833-45, 2005.
View in: PubMed
| | 14. | Rosenzweig SA. What's new in the IGF-binding proteins? Growth Horm IGF Res. .14(5):329-36, 2004. PMCID: PMC3347923
View in: PubMed
| | 15. | Robinson SA, Rosenzweig SA. Synthesis and characterization of biotinylated forms of insulin-like growth factor-1: topographical evaluation of the IGF-1/IGFBP-2 AND IGFBP-3 interface. Biochemistry. .43(36):11533-45, 2004.
View in: PubMed
| | 16. | Slomiany MG, Rosenzweig SA. IGF-1-induced VEGF and IGFBP-3 secretion correlates with increased HIF-1 alpha expression and activity in retinal pigment epithelial cell line D407. Invest Ophthalmol Vis Sci. .45(8):2838-47, 2004.
View in: PubMed
| | 17. | Slomiany MG, Rosenzweig SA. Autocrine effects of IGF-I-induced VEGF and IGFBP-3 secretion in retinal pigment epithelial cell line ARPE-19. Am J Physiol Cell Physiol. .287(3):C746-53, 2004.
View in: PubMed
| | 18. | Day TA, Davis BK, Gillespie MB, Joe JK, Kibbey M, Martin-Harris B, Neville B, Richardson MS, Rosenzweig S, Sharma AK, Smith MM, Stewart S, Stuart RK. Oral cancer treatment. Curr Treat Options Oncol. .4(1):27-41, 2003.
View in: PubMed
| | 19. | Horney MJ, Evangelista CA, Rosenzweig SA. Synthesis and characterization of insulin-like growth factor (IGF)-1 photoprobes selective for the IGF-binding proteins (IGFBPS). photoaffinity labeling of the IGF-binding domain on IGFBP-2. J Biol Chem. .276(4):2880-9, 2000.
View in: PubMed
| | 20. | Horney MJ, Shirley DW, Kurtz DT, Rosenzweig SA. Elevated glucose increases mesangial cell sensitivity to insulin-like growth factor I. Am J Physiol. .274(6 Pt 2):F1045-53, 1998.
View in: PubMed
| | 21. | Lu G, Meier KE, Jaffa AA, Rosenzweig SA, Egan BM. Oleic acid and angiotensin II induce a synergistic mitogenic response in vascular smooth muscle cells. Hypertension. .31(4):978-85, 1998.
View in: PubMed
| | 22. | Jaffa AA, Miller BS, Rosenzweig SA, Naidu PS, Velarde V, Mayfield RK. Bradykinin induces tubulin phosphorylation and nuclear translocation of MAP kinase in mesangial cells. Am J Physiol. .273(6 Pt 2):F916-24, 1997.
View in: PubMed
| | 23. | Zhang P, Miller BS, Rosenzweig SA, Bhat NR. Activation of C-jun N-terminal kinase/stress-activated protein kinase in primary glial cultures. J Neurosci Res. .46(1):114-21, 1996.
View in: PubMed
| | 24. | Lu G, Morinelli TA, Meier KE, Rosenzweig SA, Egan BM. Oleic acid-induced mitogenic signaling in vascular smooth muscle cells. A role for protein kinase C. Circ Res. .79(3):611-8, 1996.
View in: PubMed
| | 25. | Miller BS, Shankavaram UT, Horney MJ, Gore AC, Kurtz DT, Rosenzweig SA. Activation of cJun NH2-terminal kinase/stress-activated protein kinase by insulin. Biochemistry. .35(26):8769-75, 1996.
View in: PubMed
| | 26. | Law NM, Rosenzweig SA. Neuronal insulin receptors in Y79 retinoblastoma cells. Biochem Biophys Res Commun. .210(1):58-66, 1995.
View in: PubMed
| | 27. | Horio B, Law NM, Rosenzweig SA. Characterization of vasoactive intestinal peptide receptors in rabbit ciliary processes. Invest Ophthalmol Vis Sci. .36(1):192-9, 1995.
View in: PubMed
| | 28. | Law NM, Rosenzweig SA. Characterization of the G-protein linked orphan receptor GPRN1/RDC1. Biochem Biophys Res Commun. .201(1):458-65, 1994.
View in: PubMed
| | 29. | Goetzl EJ, Patel DR, Kishiyama JL, Smoll AC, Turck CW, Law NM, Rosenzweig SA, Sreedharan SP. Specific recognition of the human neuroendocrine receptor for vasoactive intestinal peptide by anti-peptide antibodies. Mol Cell Neurosci. .5(2):145-52, 1994.
View in: PubMed
| | 30. | Rosenzweig SA, Oemar BS, Law NM, Shankavaram UT, Miller BS. Insulin like growth factor 1 receptor signal transduction to the nucleus. Adv Exp Med Biol. .343:159-68, 1993.
View in: PubMed
| | 31. | Zetterström C, Benjamin A, Rosenzweig SA. Differential expression of retinal insulin receptors in STZ-induced diabetic rats. Diabetes. .41(7):818-25, 1992.
View in: PubMed
| | 32. | Oemar BS, Law NM, Rosenzweig SA. Insulin-like growth factor-1 induces tyrosyl phosphorylation of nuclear proteins. J Biol Chem. .266(36):24241-4, 1991.
View in: PubMed
| | 33. | Vignery A, Raymond MJ, Qian HY, Wang F, Rosenzweig SA. Multinucleated rat alveolar macrophages express functional receptors for calcitonin. Am J Physiol. .261(6 Pt 2):F1026-32, 1991.
View in: PubMed
| | 34. | Dardevet D, Komori K, Grunfeld C, Rosenzweig SA, Buse MG. Increased hepatic insulin proreceptor-to-receptor ratio in diabetes: a possible processing defect. Am J Physiol. .261(5 Pt 1):E562-71, 1991.
View in: PubMed
| | 35. | Zetterström C, Fang C, Benjamin A, Rosenzweig SA. Characterization of a novel receptor in toad retina with dual specificity for insulin and insulin-like growth factor I. J Neurochem. .57(4):1332-9, 1991.
View in: PubMed
| | 36. | Raymond MJ, Rosenzweig SA. Vasoactive intestinal peptide receptors on AR42J rat pancreatic acinar cells. Biochem Biophys Res Commun. .179(1):176-82, 1991.
View in: PubMed
| | 37. | Oemar BS, Foellmer HG, Hodgdon-Anandant L, Rosenzweig SA. Regulation of insulin-like growth factor I receptors in diabetic mesangial cells. J Biol Chem. .266(4):2369-73, 1991.
View in: PubMed
| | 38. | Rosenzweig SA, Zetterström C, Benjamin A. Identification of retinal insulin receptors using site-specific antibodies to a carboxyl-terminal peptide of the human insulin receptor alpha-subunit. Up-regulation of neuronal insulin receptors in diabetes. J Biol Chem. .265(29):18030-4, 1990.
View in: PubMed
| | 39. | Swedlund AP, Rosenzweig SA. Characterization of vasoactive intestinal peptide receptors in retina. Exp Eye Res. .51(3):317-23, 1990.
View in: PubMed
| | 40. | Bone EA, Rosenzweig SA. Characterization of cholecystokinin receptors in toad retina. Peptides. .9(2):373-81, 1988.
View in: PubMed
| | 41. | Madison LD, Jamieson JD, Rosenzweig SA. Heterogeneity of cholecystokinin receptors in pancreas. Biochem Biophys Res Commun. .143(2):761-7, 1987.
View in: PubMed
| | 42. | Madison LD, Rosenzweig SA, Jamieson JD. Use of the heterobifunctional cross-linker m-maleimidobenzoyl N-hydroxysuccinimide ester to affinity label cholecystokinin binding proteins on rat pancreatic plasma membranes. J Biol Chem. .259(23):14818-23, 1984.
View in: PubMed
| | 43. | Rosenzweig SA, Madison LD, Jamieson JD. Analysis of cholecystokinin-binding proteins using endo-beta-N-acetylglucosaminidase F. J Cell Biol. .99(3):1110-6, 1984. PMCID: PMC2113376
View in: PubMed
|
|