Research Interest:
Lung cancer; Benign and malignant esophageal disease; Biology of lung cancer metastases
Positions: Medical Co-Director, Biorepository & Research Pathology Services Shared Resource, Hollings Cancer Center, Medical University of South Carolina
Selected Publications:
| 1. | Denlinger CE. Invited commentary. Ann Thorac Surg. .95(3):992-3, 2013.
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| | 2. | Denlinger CE. Invited commentary. Ann Thorac Surg. .94(6):2101-2, 2012.
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| | 3. | Denlinger CE, Thompson RK. Molecular basis of esophageal cancer development and progression. Surg Clin North Am. .92(5):1089-103, 2012.
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| | 4. | Denlinger CE, Reed CE. Contemporary management of esophageal malignancy. Surg Clin North Am. .92(5):xvii-xviii, 2012.
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| | 5. | Griffin JM, Reed CE, Denlinger CE. Utility of restaging endoscopic ultrasound after neoadjuvant therapy for esophageal cancer. Ann Thorac Surg. .93(6):1855-9; discussion 1860, 2012.
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| | 6. | Paoletti L, Pastis NJ, Denlinger CE, Silvestri GA. A decade of advances in treatment of early-stage lung cancer. Clin Chest Med. .32(4):827-38, 2011. PMCID: PMC3403691
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| | 7. | Denlinger CE. The survival benefit of lung transplantation among patients with advanced pulmonary diseases. J S C Med Assoc. .107(4):133-8, 2011.
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| | 8. | McLaughlin CW, Person TD, Denlinger CE. Management of acute esophageal necrosis syndrome. J Thorac Cardiovasc Surg. .141(3):e23-4, 2011.
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| | 9. | Denlinger CE, Ikonomidis JS, Reed CE, Spinale FG. Epithelial to mesenchymal transition: the doorway to metastasis in human lung cancers. J Thorac Cardiovasc Surg. .140(3):505-13, 2010.
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| | 10. | Denlinger CE. A balanced perspective for management of tracheal salivary gland-type carcinomas. J Thorac Cardiovasc Surg. .140(2):394, 2010.
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| | 11. | Eckhouse SR, Person TD, Reed CE, Ikonomidis JS, Denlinger CE. Sternoclavicular joint infection necessitating through skin and lung parenchyma. Ann Thorac Surg. .90(1):309-11, 2010.
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| | 12. | Denlinger CE, Fernandez F, Meyers BF, Pratt W, Zoole JB, Patterson GA, Krupnick AS, Kreisel D, Crabtree T. Lymph node evaluation in video-assisted thoracoscopic lobectomy versus lobectomy by thoracotomy. Ann Thorac Surg. .89(6):1730-5; discussion 1736, 2010.
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| | 13. | Crabtree TD, Denlinger CE, Meyers BF, El Naqa I, Zoole J, Krupnick AS, Kreisel D, Patterson GA, Bradley JD. Stereotactic body radiation therapy versus surgical resection for stage I non-small cell lung cancer. J Thorac Cardiovasc Surg. .140(2):377-86, 2010.
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| | 14. | Fernandez FG, Denlinger CE, Crabtree TD. Primary non-Hodgkin's lymphoma of the trachea. J Thorac Oncol. .5(3):403-4, 2010.
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| | 15. | Fernandez FG, Denlinger CE, Patterson GA, Kreisel D, Krupnick AS. Massive bilateral chylothoraces complicating mediastinal granulomatous disease. Ann Thorac Surg. .88(3):1012-3, 2009.
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| | 16. | Denlinger CE, Meyers BF. Update on lung transplantation for emphysema. Thorac Surg Clin. .19(2):275-83, 2009.
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| | 17. | Denlinger CE, Fernandez FG, Patterson GA, Kreisel D. Fibrosing mediastinitis associated with complete occlusion of the left main pulmonary artery. Ann Thorac Surg. .87(1):323, 2009.
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| | 18. | Deacon DH, Hogan KT, Swanson EM, Chianese-Bullock KA, Denlinger CE, Czarkowski AR, Schrecengost RS, Patterson JW, Teague MW, Slingluff CL. The use of gamma-irradiation and ultraviolet-irradiation in the preparation of human melanoma cells for use in autologous whole-cell vaccines. BMC Cancer. .8:360, 2008. PMCID: PMC2612687
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| | 19. | Denlinger CE, Veeramachaneni N, Krupnick AS, Patterson GA, Kreisel D. Nonoperative management of large tracheal injuries. J Thorac Cardiovasc Surg. .136(3):782-3, 783.e1, 2008.
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| | 20. | Denlinger CE, Slingluff CL, Mihm MC, Patterson JW. Extensive neurocristic hamartoma with skeletal muscle involvement. J Cutan Pathol. .34(8):634-9, 2007.
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| | 21. | Young JS, Stokes JB, Denlinger CE, Dubose JE. Proactive versus reactive: the effect of experience on performance in a critical care simulator. Am J Surg. .193(1):100-4, 2007.
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| | 22. | Smith PW, Denlinger CE, Jones DR. Novel targeted therapies for non-small cell lung cancer. Thorac Surg Clin. .16(4):353-66, 2006.
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| | 23. | Liu Y, Denlinger CE, Rundall BK, Smith PW, Jones DR. Suberoylanilide hydroxamic acid induces Akt-mediated phosphorylation of p300, which promotes acetylation and transcriptional activation of RelA/p65. J Biol Chem. .281(42):31359-68, 2006.
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| | 24. | Jones DR, Daniel TM, Denlinger CE, Rundall BK, Smolkin ME, Wick MR. Stage IB nonsmall cell lung cancers: are they all the same? Ann Thorac Surg. .81(6):1958-62; discussion 1962, 2006.
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| | 25. | Denlinger CE, Rundall BK, Jones DR. Inhibition of phosphatidylinositol 3-kinase/Akt and histone deacetylase activity induces apoptosis in non-small cell lung cancer in vitro and in vivo. J Thorac Cardiovasc Surg. .130(5):1422-9, 2005.
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| | 26. | Rundall BK, Denlinger CE, Parrino GP, Foley EF, Jones DR. Laparoscopic gastric bypass complicated by gastric pouch necrosis: considerations in gastroesophageal reconstruction. J Gastrointest Surg. .9(7):938-40, 2005.
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| | 27. | Rundall BK, Denlinger CE, Jones DR. Suberoylanilide hydroxamic acid combined with gemcitabine enhances apoptosis in non-small cell lung cancer. Surgery. .138(2):360-7, 2005.
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| | 28. | Denlinger CE, Rundall BK, Jones DR. Proteasome inhibition sensitizes non-small cell lung cancer to histone deacetylase inhibitor-induced apoptosis through the generation of reactive oxygen species. J Thorac Cardiovasc Surg. .128(5):740-8, 2004.
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| | 29. | Denlinger CE, Rundall BK, Keller MD, Jones DR. Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis. Ann Thorac Surg. .78(4):1207-14; discussion 1207-14, 2004.
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| | 30. | Rundall BK, Denlinger CE, Jones DR. Combined histone deacetylase and NF-kappaB inhibition sensitizes non-small cell lung cancer to cell death. Surgery. .136(2):416-25, 2004.
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| | 31. | Denlinger CE, Keller MD, Mayo MW, Broad RM, Jones DR. Combined proteasome and histone deacetylase inhibition in non-small cell lung cancer. J Thorac Cardiovasc Surg. .127(4):1078-86, 2004.
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| | 32. | Denlinger CE, Rundall BK, Jones DR. Modulation of antiapoptotic cell signaling pathways in non-small cell lung cancer: the role of NF-kappaB. Semin Thorac Cardiovasc Surg. .16(1):28-39, 2004.
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| | 33. | Jones DR, Stiles BM, Denlinger CE, Antippa P, Daniel TM. Pulmonary segmentectomy: results and complications. Ann Thorac Surg. .76(2):343-8; discussion 348-9, 2003.
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| | 34. | Mayo MW, Denlinger CE, Broad RM, Yeung F, Reilly ET, Shi Y, Jones DR. Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway. J Biol Chem. .278(21):18980-9, 2003.
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| | 35. | Denlinger CE, Egan TM, Jones DR. Acquired systemic-to-pulmonary arteriovenous malformation secondary to Mycobacterium tuberculosis empyema. Ann Thorac Surg. .74(4):1229-31, 2002.
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